Damien Hirst has continually challenged the boundaries between art, science, the media and popular culture. A 12-foot tiger shark,a cow and her calf sawn in two, pharmacy bottles, house paint poured onto spinning canvases, cigarette butts, medicine cabinets, office furniture, medical instruments, butterflies and tropical fish, and, most recently, a diamond-encrusted skull are just some of the means Damien Hirst employs to communicate his unflinching view of the ambiguity at the heart of human experience.